Kawakami, Hiromasa MD; Nakajima, Daisuke MD; Mihara, Takahiro MD, PhD; Sato, Hitoshi MD; Goto, Takahisa MD, PhD
Anesthesia & Analgesia: September 2019 – Volume 129 – Issue 3 – p 689-700
Shivering is common during the perioperative period. It can increase the oxygen demand of the body and may induce myocardial ischemia. Despite rigorous efforts to prevent hypothermia, many patients suffer from perioperative shivering. Younger age, endoprosthetic surgery, low core temperature, and longer duration of surgery were considered as risk factors for postoperative shivering in a previous trial. Pharmacological intervention may reduce the incidence of shivering. Drugs such as dexmedetomidine, 5-hydroxytryptamine 3 receptor antagonists,4and meperidine have been demonstrated to have antishivering effects, but their cost is prohibitive, and their safety is questionable.
Perioperative magnesium may reduce the need for anesthetic agents,neuromuscular blocking agents, and opioids. In a previous meta-analysis,5 combined data from 3 trials showed that magnesium reduced the incidence of shivering. Results from other meta-analyses are inconsistent. Read More